diff --git a/backend/open_webui/apps/audio/main.py b/backend/open_webui/apps/audio/main.py
index 8f643ffd3..0eee533bd 100644
--- a/backend/open_webui/apps/audio/main.py
+++ b/backend/open_webui/apps/audio/main.py
@@ -19,6 +19,8 @@ from open_webui.config import (
     AUDIO_TTS_OPENAI_API_KEY,
     AUDIO_TTS_SPLIT_ON,
     AUDIO_TTS_VOICE,
+    AUDIO_TTS_AZURE_SPEECH_REGION,
+    AUDIO_TTS_AZURE_SPEECH_OUTPUT_FORMAT,
     CACHE_DIR,
     CORS_ALLOW_ORIGIN,
     WHISPER_MODEL,
@@ -62,6 +64,9 @@ app.state.config.TTS_VOICE = AUDIO_TTS_VOICE
 app.state.config.TTS_API_KEY = AUDIO_TTS_API_KEY
 app.state.config.TTS_SPLIT_ON = AUDIO_TTS_SPLIT_ON
 
+app.state.config.TTS_AZURE_SPEECH_REGION = AUDIO_TTS_AZURE_SPEECH_REGION
+app.state.config.TTS_AZURE_SPEECH_OUTPUT_FORMAT = AUDIO_TTS_AZURE_SPEECH_OUTPUT_FORMAT
+
 # setting device type for whisper model
 whisper_device_type = DEVICE_TYPE if DEVICE_TYPE and DEVICE_TYPE == "cuda" else "cpu"
 log.info(f"whisper_device_type: {whisper_device_type}")
@@ -78,6 +83,8 @@ class TTSConfigForm(BaseModel):
     MODEL: str
     VOICE: str
     SPLIT_ON: str
+    AZURE_SPEECH_REGION: str
+    AZURE_SPEECH_OUTPUT_FORMAT: str
 
 
 class STTConfigForm(BaseModel):
@@ -130,6 +137,8 @@ async def get_audio_config(user=Depends(get_admin_user)):
             "MODEL": app.state.config.TTS_MODEL,
             "VOICE": app.state.config.TTS_VOICE,
             "SPLIT_ON": app.state.config.TTS_SPLIT_ON,
+            "AZURE_SPEECH_REGION": app.state.config.TTS_AZURE_SPEECH_REGION,
+            "AZURE_SPEECH_OUTPUT_FORMAT": app.state.config.TTS_AZURE_SPEECH_OUTPUT_FORMAT,
         },
         "stt": {
             "OPENAI_API_BASE_URL": app.state.config.STT_OPENAI_API_BASE_URL,
@@ -151,6 +160,10 @@ async def update_audio_config(
     app.state.config.TTS_MODEL = form_data.tts.MODEL
     app.state.config.TTS_VOICE = form_data.tts.VOICE
     app.state.config.TTS_SPLIT_ON = form_data.tts.SPLIT_ON
+    app.state.config.TTS_AZURE_SPEECH_REGION = form_data.tts.AZURE_SPEECH_REGION
+    app.state.config.TTS_AZURE_SPEECH_OUTPUT_FORMAT = (
+        form_data.tts.AZURE_SPEECH_OUTPUT_FORMAT
+    )
 
     app.state.config.STT_OPENAI_API_BASE_URL = form_data.stt.OPENAI_API_BASE_URL
     app.state.config.STT_OPENAI_API_KEY = form_data.stt.OPENAI_API_KEY
@@ -166,6 +179,8 @@ async def update_audio_config(
             "MODEL": app.state.config.TTS_MODEL,
             "VOICE": app.state.config.TTS_VOICE,
             "SPLIT_ON": app.state.config.TTS_SPLIT_ON,
+            "AZURE_SPEECH_REGION": app.state.config.TTS_AZURE_SPEECH_REGION,
+            "AZURE_SPEECH_OUTPUT_FORMAT": app.state.config.TTS_AZURE_SPEECH_OUTPUT_FORMAT,
         },
         "stt": {
             "OPENAI_API_BASE_URL": app.state.config.STT_OPENAI_API_BASE_URL,
@@ -301,6 +316,42 @@ async def speech(request: Request, user=Depends(get_verified_user)):
                 detail=error_detail,
             )
 
+    elif app.state.config.TTS_ENGINE == "azure":
+        payload = None
+        try:
+            payload = json.loads(body.decode("utf-8"))
+        except Exception as e:
+            log.exception(e)
+            raise HTTPException(status_code=400, detail="Invalid JSON payload")
+
+        region = app.state.config.TTS_AZURE_SPEECH_REGION
+        language = app.state.config.TTS_VOICE
+        locale = "-".join(app.state.config.TTS_VOICE.split("-")[:1])
+        output_format = app.state.config.TTS_AZURE_SPEECH_OUTPUT_FORMAT
+        url = f"https://{region}.tts.speech.microsoft.com/cognitiveservices/v1"
+
+        headers = {
+            "Ocp-Apim-Subscription-Key": app.state.config.TTS_API_KEY,
+            "Content-Type": "application/ssml+xml",
+            "X-Microsoft-OutputFormat": output_format,
+        }
+
+        data = f"""<speak version="1.0" xmlns="http://www.w3.org/2001/10/synthesis" xml:lang="{locale}">
+                <voice name="{language}">{payload["input"]}</voice>
+            </speak>"""
+
+        response = requests.post(url, headers=headers, data=data)
+
+        if response.status_code == 200:
+            with open(file_path, "wb") as f:
+                f.write(response.content)
+            return FileResponse(file_path)
+        else:
+            log.error(f"Error synthesizing speech - {response.reason}")
+            raise HTTPException(
+                status_code=500, detail=f"Error synthesizing speech - {response.reason}"
+            )
+
 
 @app.post("/transcriptions")
 def transcribe(
@@ -478,6 +529,21 @@ def get_available_voices() -> dict:
         except Exception:
             # Avoided @lru_cache with exception
             pass
+    elif app.state.config.TTS_ENGINE == "azure":
+        try:
+            region = app.state.config.TTS_AZURE_SPEECH_REGION
+            url = f"https://{region}.tts.speech.microsoft.com/cognitiveservices/voices/list"
+            headers = {"Ocp-Apim-Subscription-Key": app.state.config.TTS_API_KEY}
+
+            response = requests.get(url, headers=headers)
+            response.raise_for_status()
+            voices = response.json()
+            for voice in voices:
+                ret[voice["ShortName"]] = (
+                    f"{voice['DisplayName']} ({voice['ShortName']})"
+                )
+        except requests.RequestException as e:
+            log.error(f"Error fetching voices: {str(e)}")
 
     return ret
 
diff --git a/backend/open_webui/config.py b/backend/open_webui/config.py
index 439e82e43..7ad10ccdc 100644
--- a/backend/open_webui/config.py
+++ b/backend/open_webui/config.py
@@ -1472,3 +1472,17 @@ AUDIO_TTS_SPLIT_ON = PersistentConfig(
     "audio.tts.split_on",
     os.getenv("AUDIO_TTS_SPLIT_ON", "punctuation"),
 )
+
+AUDIO_TTS_AZURE_SPEECH_REGION = PersistentConfig(
+    "AUDIO_TTS_AZURE_SPEECH_REGION",
+    "audio.tts.azure.speech_region",
+    os.getenv("AUDIO_TTS_AZURE_SPEECH_REGION", "eastus"),
+)
+
+AUDIO_TTS_AZURE_SPEECH_OUTPUT_FORMAT = PersistentConfig(
+    "AUDIO_TTS_AZURE_SPEECH_OUTPUT_FORMAT",
+    "audio.tts.azure.speech_output_format",
+    os.getenv(
+        "AUDIO_TTS_AZURE_SPEECH_OUTPUT_FORMAT", "audio-24khz-160kbitrate-mono-mp3"
+    ),
+)
diff --git a/src/lib/components/admin/Settings/Audio.svelte b/src/lib/components/admin/Settings/Audio.svelte
index 1c114c9dd..040bc5e1a 100644
--- a/src/lib/components/admin/Settings/Audio.svelte
+++ b/src/lib/components/admin/Settings/Audio.svelte
@@ -31,6 +31,8 @@
 	let TTS_MODEL = '';
 	let TTS_VOICE = '';
 	let TTS_SPLIT_ON: TTS_RESPONSE_SPLIT = TTS_RESPONSE_SPLIT.PUNCTUATION;
+	let TTS_AZURE_SPEECH_REGION = '';
+	let TTS_AZURE_SPEECH_OUTPUT_FORMAT = '';
 
 	let STT_OPENAI_API_BASE_URL = '';
 	let STT_OPENAI_API_KEY = '';
@@ -87,7 +89,9 @@
 				ENGINE: TTS_ENGINE,
 				MODEL: TTS_MODEL,
 				VOICE: TTS_VOICE,
-				SPLIT_ON: TTS_SPLIT_ON
+				SPLIT_ON: TTS_SPLIT_ON,
+				AZURE_SPEECH_REGION: TTS_AZURE_SPEECH_REGION,
+				AZURE_SPEECH_OUTPUT_FORMAT: TTS_AZURE_SPEECH_OUTPUT_FORMAT
 			},
 			stt: {
 				OPENAI_API_BASE_URL: STT_OPENAI_API_BASE_URL,
@@ -120,6 +124,9 @@
 
 			TTS_SPLIT_ON = res.tts.SPLIT_ON || TTS_RESPONSE_SPLIT.PUNCTUATION;
 
+			TTS_AZURE_SPEECH_OUTPUT_FORMAT = res.tts.AZURE_SPEECH_OUTPUT_FORMAT;
+			TTS_AZURE_SPEECH_REGION = res.tts.AZURE_SPEECH_REGION;
+
 			STT_OPENAI_API_BASE_URL = res.stt.OPENAI_API_BASE_URL;
 			STT_OPENAI_API_KEY = res.stt.OPENAI_API_KEY;
 
@@ -224,6 +231,7 @@
 							<option value="">{$i18n.t('Web API')}</option>
 							<option value="openai">{$i18n.t('OpenAI')}</option>
 							<option value="elevenlabs">{$i18n.t('ElevenLabs')}</option>
+							<option value="azure">{$i18n.t('Azure AI Speech')}</option>
 						</select>
 					</div>
 				</div>
@@ -252,6 +260,23 @@
 							/>
 						</div>
 					</div>
+				{:else if TTS_ENGINE === 'azure'}
+					<div>
+						<div class="mt-1 flex gap-2 mb-1">
+							<input
+								class="flex-1 w-full rounded-lg py-2 pl-4 text-sm bg-gray-50 dark:text-gray-300 dark:bg-gray-850 outline-none"
+								placeholder={$i18n.t('API Key')}
+								bind:value={TTS_API_KEY}
+								required
+							/>
+							<input
+								class="flex-1 w-full rounded-lg py-2 pl-4 text-sm bg-gray-50 dark:text-gray-300 dark:bg-gray-850 outline-none"
+								placeholder={$i18n.t('Azure Region')}
+								bind:value={TTS_AZURE_SPEECH_REGION}
+								required
+							/>
+						</div>
+					</div>
 				{/if}
 
 				<hr class=" dark:border-gray-850 my-2" />
@@ -359,6 +384,49 @@
 							</div>
 						</div>
 					</div>
+				{:else if TTS_ENGINE === 'azure'}
+					<div class=" flex gap-2">
+						<div class="w-full">
+							<div class=" mb-1.5 text-sm font-medium">{$i18n.t('TTS Voice')}</div>
+							<div class="flex w-full">
+								<div class="flex-1">
+									<input
+										list="voice-list"
+										class="w-full rounded-lg py-2 px-4 text-sm bg-gray-50 dark:text-gray-300 dark:bg-gray-850 outline-none"
+										bind:value={TTS_VOICE}
+										placeholder="Select a voice"
+									/>
+
+									<datalist id="voice-list">
+										{#each voices as voice}
+											<option value={voice.id}>{voice.name}</option>
+										{/each}
+									</datalist>
+								</div>
+							</div>
+						</div>
+						<div class="w-full">
+							<div class=" mb-1.5 text-sm font-medium">
+								{$i18n.t('Output format')}
+								<a
+									href="https://learn.microsoft.com/en-us/azure/ai-services/speech-service/rest-text-to-speech?tabs=streaming#audio-outputs"
+									target="_blank"
+								>
+									<small>{$i18n.t('Available list')}</small>
+								</a>
+							</div>
+							<div class="flex w-full">
+								<div class="flex-1">
+									<input
+										list="tts-model-list"
+										class="w-full rounded-lg py-2 px-4 text-sm bg-gray-50 dark:text-gray-300 dark:bg-gray-850 outline-none"
+										bind:value={TTS_AZURE_SPEECH_OUTPUT_FORMAT}
+										placeholder="Select a output format"
+									/>
+								</div>
+							</div>
+						</div>
+					</div>
 				{/if}
 
 				<hr class="dark:border-gray-850 my-2" />